CKDdb-logoCKDdb - Molecule ID A0397

geneAtp6v1a
nameProtein Atp6v1a
speciesRattus norvegicus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
VATA_MOUSED4A133ENSRNOG00000001992685232Rn.1431607027

Functions and classifications

GOC:proton-transporting V-type ATPase, V1 domain, F:ATP binding, F:proton-transporting ATPase activity, rotational mechanism, P:ATP hydrolysis coupled proton transport, C:apical plasma membrane, C:cytosol, C:microvillus, C:mitochondrion, F:hydrogen ion transporting ATP synthase activity, rotational mechanism
UniProtComplete proteome, Hydrogen ion transport, Ion transport, Reference proteome, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17021608Rattus norvegicus12urineexosomeAKI (AKI)0.5< 0.05MALDI-TOF-TOF17021608
Exp17609286Mus musculus10kidneyglomeruliDiabetes (diabetic nephropathy in Type 1 diabetes) < 0.05MALDI-TOF-MS17609286
Exp17609286Mus musculus10kidneyglomeruliDiabetes (diabetic nephropathy in Type 1 diabetes)up< 0.05MALDI-TOF-MS17609286
Exp19688724Mus musculus kidneypodocytesHigh_glucose_induced (High glucose in vitro model)0.4< 0.05MALDI-TOF-MS19688724
Exp24316357Rattus norvegicus kidneyproximal tubule cellsureteral_obstruction (kidney obstruction in vitro model)2.050.005821084LC-MS/MS24316357
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.458.19E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium