CKDdb-logoCKDdb - Molecule ID A0394

geneATP5O, ATPO
nameATP synthase subunit O
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATPO_HUMANP48047ENSG00000241837539Hs.409140600828

Functions and classifications

GOC:mitochondrial proton-transporting ATP synthase complex, C:plasma membrane, F:drug binding, F:proton-transporting ATP synthase activity, rotational mechanism, F:transmembrane transporter activity, P:ATP catabolic process, P:mitochondrial ATP synthesis coupled proton transport, P:respiratory electron transport chain, F:proton-transporting ATP synthase activity, rotational mechanism, P:ATP synthesis coupled proton transport, C:membrane, C:mitochondrial proton-transporting ATP synthase complex, coupling factor F(o), F:hydrogen ion transporting ATP synthase activity, rotational mechanism, F:steroid binding, F:hydrogen ion transporting ATP synthase activity, rotational mechanism
UniProtAcetylation, ATP synthesis, Complete proteome, Direct protein sequencing, Hydrogen ion transport, Ion transport, Membrane, Mitochondrion, Mitochondrion inner membrane, Polymorphism, Reference proteome, Transit peptide, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17609286Mus musculus10kidneyglomeruliDiabetes (diabetic nephropathy in Type 1 diabetes) < 0.05MALDI-TOF-MS17609286
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.440.01cDNA microarray19099603
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)6.135.34E-13RNA microarray19698090
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.35< 0.05RNA microarray21752957

Compile date 08-10-2018© iMODE-CKD consortium