CKDdb-logoCKDdb - Molecule ID A0391

geneATP5J, ATP5A, ATPM
nameATP synthase coupling factor 6
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATP5J_HUMANP18859ENSG00000154723522Hs.246310603152

Functions and classifications

GOC:mitochondrial proton-transporting ATP synthase complex, C:mitochondrial proton-transporting ATP synthase complex, coupling factor F(o), F:hydrogen ion transmembrane transporter activity, F:transmembrane transporter activity, P:ATP catabolic process, P:mitochondrial ATP synthesis coupled proton transport, P:respiratory electron transport chain, C:mitochondrial proton-transporting ATP synthase complex, coupling factor F(o), C:mitochondrion, P:ATP synthesis coupled proton transport
UniProtAcetylation, Alternative splicing, CF(0), Complete proteome, Direct protein sequencing, Hydrogen ion transport, Ion transport, Membrane, Mitochondrion, Mitochondrion inner membrane, Reference proteome, Transit peptide, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.380.01cDNA microarray19099603
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)8.927.27E-14RNA microarray19698090
Exp19845401Mus musculus32eyesretinaDiabetes (diabetic retinopathy)4.09< 0.05LC-MS/MS19845401
Exp20093355Homo sapiens33kidney Fibrosis (Interstitial fibrosis and tubular atrophy)down MS/MS, LTQ LX linear ion trap20093355
Exp20348205aRattus norvegicus10bloodplasmaDiabetes (Gestational Diabetes)0.74< 0.05RP-nano-LC-ESI-MS/MS20348205
Exp25770168Homo sapiens17bloodmononuclear cellsGlomerulonephritis (IgA nephropathy)0.180.002RNA microarray25770168

Compile date 08-10-2018© iMODE-CKD consortium