CKDdb-logoCKDdb - Molecule ID A0387

geneATP5H, My032
nameATP synthase D chain
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
ATP5H_HUMANO75947ENSG0000016786310476Hs.514465

Functions and classifications

GOC:mitochondrial proton-transporting ATP synthase complex, C:mitochondrial proton-transporting ATP synthase complex, coupling factor F(o), F:hydrogen ion transmembrane transporter activity, F:transmembrane transporter activity, P:ATP catabolic process, P:mitochondrial ATP synthesis coupled proton transport, P:respiratory electron transport chain, C:mitochondrial proton-transporting ATP synthase complex, coupling factor F(o), P:ATP synthesis coupled proton transport, P:ATP synthesis coupled proton transport
UniProtAcetylation, Alternative splicing, CF(0), Complete proteome, Direct protein sequencing, Hydrogen ion transport, Ion transport, Membrane, Mitochondrion, Mitochondrion inner membrane, Reference proteome, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17609286Mus musculus10kidneyglomeruliDiabetes (diabetic nephropathy in Type 1 diabetes)up< 0.05MALDI-TOF-MS17609286
Exp19369687Mus musculus kidneyproximal tubule cellsCyclosporine_A_induced (Ciclosporine A in vitro model)0.74< 0.005MALDI TOF/TOF19369687
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)2.30.0000003RNA microarray19698090
Exp20716515Homo sapiens kidneyproximal tubule epithelial cellFibrosis (TGFbeta in vitro model)0.790.0011MALDI-TOF20716515
Exp24497609Rattus norvegicus kidneyglomeruliPuromycin_induced (Puromycin nephropathy model)1.62< 0.05LC-MS/MS24497609
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.453.73E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium