CKDdb-logoCKDdb - Molecule ID A0381

geneATP5E
nameATP synthase epsilon chain
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATP5E_HUMANP56381ENSG00000124172514Hs.177530606153, 614053

Functions and classifications

GOC:mitochondrial matrix, C:mitochondrial proton-transporting ATP synthase complex, C:mitochondrial proton-transporting ATP synthase complex, catalytic core F(1), F:proton-transporting ATP synthase activity, rotational mechanism, F:proton-transporting ATPase activity, rotational mechanism, F:transmembrane transporter activity, P:ATP catabolic process, P:mitochondrial ATP synthesis coupled proton transport, P:respiratory electron transport chain, F:hydrogen ion transporting ATP synthase activity, rotational mechanism
UniProtAcetylation, ATP synthesis, CF(1), Complete proteome, Disease mutation, Hydrogen ion transport, Hydrolase, Ion transport, Membrane, Mitochondrion, Mitochondrion inner membrane, Reference proteome, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.370.01cDNA microarray19099603
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)2.750.000000122RNA microarray19698090
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.463.63E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium