CKDdb-logoCKDdb - Molecule ID A0379

geneATP5C1, ATP5C, ATP5CL1
nameATP synthase gamma chain
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATPG_HUMANP36542ENSG00000165629509Hs.271135108729

Functions and classifications

GOC:mitochondrial matrix, C:mitochondrial proton-transporting ATP synthase complex, catalytic core F(1), F:proton-transporting ATP synthase activity, rotational mechanism, F:proton-transporting ATPase activity, rotational mechanism, F:transmembrane transporter activity, P:ATP catabolic process, P:mitochondrial ATP synthesis coupled proton transport, P:oxidative phosphorylation, P:respiratory electron transport chain, C:mitochondrial inner membrane, C:proton-transporting ATP synthase complex, catalytic core F(1), P:ATP synthesis coupled proton transport, F:hydrogen ion transporting ATP synthase activity, rotational mechanism
UniProtAcetylation, Alternative splicing, ATP synthesis, CF(1), Complete proteome, Direct protein sequencing, Hydrogen ion transport, Ion transport, Membrane, Mitochondrion, Mitochondrion inner membrane, Reference proteome, Transit peptide, Transport, Phosphoprotein
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.50cDNA microarray19099603
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.180.00000482RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)4.321.70E-10RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)6.163.59E-13RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)7.294.71E-11RNA microarray19698090
Exp23809614aHomo sapiens83bloodwholeChronic_Renal_Insufficiency (End-stage renal failure)0.224.50E-14RNA microarray23809614
Exp23809614bHomo sapiens32bloodwholeChronic_Renal_Insufficiency (End-stage renal failure)0.21.53E-09RNA microarray23809614
Exp24090408Rattus norvegicus28kidneycortexChronic_Renal_Insufficiency (early_stage_CKD)down 2DE, LC-MS/MS24090408

Compile date 08-10-2018© iMODE-CKD consortium