CKDdb-logoCKDdb - Molecule ID A0378

geneAtp5b
nameATP synthase subunit beta, mitochondrial
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATPB_MOUSEP56480ENSMUSG0000002539311947Mm.238973102910

Functions and classifications

GOC:cell surface, C:mitochondrial inner membrane, C:mitochondrial nucleoid, C:mitochondrial proton-transporting ATP synthase complex, C:mitochondrion, C:plasma membrane, C:proton-transporting ATP synthase complex, catalytic core F(1), F:ATP binding, F:proton-transporting ATP synthase activity, rotational mechanism, F:proton-transporting ATPase activity, rotational mechanism, P:angiogenesis, P:ATP hydrolysis coupled proton transport, P:ATP synthesis coupled proton transport, P:lipid metabolic process, P:negative regulation of cell adhesion involved in substrate-bound cell migration, P:regulation of intracellular pH, C:mitochondrial proton-transporting ATP synthase complex, catalytic core F(1), F:calcium ion binding, F:eukaryotic cell surface binding, F:hydrogen ion transporting ATP synthase activity, rotational mechanism, F:hydrogen-exporting ATPase activity, phosphorylative mechanism, F:lipoprotein particle receptor activity, P:ADP biosynthetic process
UniProtAcetylation, ATP synthesis, ATP-binding, CF(1), Complete proteome, Direct protein sequencing, Hydrogen ion transport, Hydrolase, Ion transport, Membrane, Mitochondrion, Mitochondrion inner membrane, Nucleotide-binding, Phosphoprotein, Reference proteome, Transit peptide, Transport
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.480cDNA microarray19099603
Exp19688724Mus musculus kidneypodocytesHigh_glucose_induced (High glucose in vitro model)0< 0.05MALDI-TOF-MS19688724
Exp20348205aRattus norvegicus10bloodplasmaDiabetes (Gestational Diabetes)0.87< 0.05RP-nano-LC-ESI-MS/MS20348205
Exp22172726Homo sapiens20kidneyglomeruliDiabetes (type 2 diabetic nephropathy)0.90.0259QSTAR Elite LC-MS/MS22172726

Compile date 08-10-2018© iMODE-CKD consortium