CKDdb-logoCKDdb - Molecule ID A0344

geneATP1B1, ATP1B
nameSodium/potassium-transporting ATPase beta-1 chain
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AT1B1_HUMANP05026ENSG00000143153481Hs.291196182330

Functions and classifications

GOC:apical plasma membrane, C:basolateral plasma membrane, C:caveola, C:sodium:potassium-exchanging ATPase complex, F:sodium:potassium-exchanging ATPase activity, P:blood coagulation, P:cell adhesion, P:leukocyte migration, P:response to hypoxia, P:potassium ion transport, P:sodium ion transport, P:ATP catabolic process, P:potassium ion transmembrane transport, P:sodium ion transmembrane transport, P:ATP biosynthetic process, C:integral to membrane, C:membrane
UniProtAlternative splicing, Cell adhesion, Cell membrane, Complete proteome, Disulfide bond, Glycoprotein, Ion transport, Membrane, Phosphoprotein, Potassium, Potassium transport, Reference proteome, Signal-anchor, Sodium, Sodium transport, Sodium/potassium transport, Transmembrane, Transmembrane helix, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)2.240.0197RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)3.080.000859RNA microarray19698090
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.480.000113537RNA microarray20019191
Exp21544065aRattus norvegicus17kidney Diabetes (diabetic nephropathy in T1D)0.63< 0.001MALDI-TOF/TOF21544065
Exp21544065bRattus norvegicus17kidney Diabetes (diabetic nephropathy in T1D)0.49< 0.001MALDI-TOF/TOF21544065
Exp21544065cRattus norvegicus17kidney Diabetes (diabetic nephropathy in T1D)0.92< 0.001MALDI-TOF/TOF21544065
Exp23344851Rattus norvegicus14urineexosomeDiabetes (diabetic nephropathy)2.25 nLC-ESI-UHR-QToF-MS/MS23344851
Exp23505438aHomo sapiens kidneyproximal tubular cellsDiabetes (diabetic nephropathy)1.660.016cDNA microarray23505438
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.477.82E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium