CKDdb-logoCKDdb - Molecule ID A0253

geneAP2B1, ADTB2, CLAPB1
nameAdapter-related protein complex 2 beta 1 subunit
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AP2B1_HUMANP63010ENSG00000006125163Hs.514819601025

Functions and classifications

GOC:clathrin adaptor complex, C:clathrin-coated endocytic vesicle membrane, C:coated pit, C:cytosol, C:plasma membrane, C:trans-Golgi network, F:protein transporter activity, P:antigen processing and presentation of exogenous peptide antigen via MHC class II, P:axon guidance, P:clathrin coat assembly, P:endocytosis, P:epidermal growth factor receptor signaling pathway, P:intracellular protein transport, P:negative regulation of epidermal growth factor receptor signaling pathway, P:neurotrophin TRK receptor signaling pathway, P:regulation of defense response to virus by virus, P:synaptic transmission, P:viral process, P:vesicle-mediated transport, P:nerve growth factor receptor signaling pathway, P:neurotransmitter secretion, P:synaptic vesicle endocytosis, P:viral reproduction, C:membrane coat, C:clathrin coat
UniProt3D-structure, Acetylation, Alternative splicing, Cell membrane, Coated pit, Complete proteome, Endocytosis, Membrane, Phosphoprotein, Protein transport, Reference proteome, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)2.580.00274RNA microarray19698090
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)2.93< 0.05RNA microarray21752957
Exp25770168Homo sapiens17bloodmononuclear cellsGlomerulonephritis (IgA nephropathy)5.280.006RNA microarray25770168
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)3.350.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium