CKDdb-logoCKDdb - Molecule ID A0235

geneACTR2, ARP2
nameActin-like protein 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARP2_HUMANP61160ENSP0000026064110097Hs.643727604221

Functions and classifications

GOC:actin cap, C:Arp2/3 protein complex, C:cell projection, C:cytosol, F:ATP binding, P:Arp2/3 complex-mediated actin nucleation, P:asymmetric cell division, P:cellular component movement, P:cytoplasmic transport, P:establishment or maintenance of cell polarity, P:Fc-gamma receptor signaling pathway involved in phagocytosis, P:innate immune response, P:meiotic cytokinesis, P:spindle localization, C:cytoplasm, P:actin cytoskeleton organization, P:cytokinesis after meiosis, P:meiotic cell cycle
UniProtAcetylation, Actin-binding, Alternative splicing, ATP-binding, Cell projection, Complete proteome, Cytoplasm, Cytoskeleton, Direct protein sequencing, Nucleotide-binding, Reference proteome
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)3.273.23E-06RNA microarray20019191
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)5.87< 0.05RNA microarray21752957
Exp24172336Mus musculus6kidneycortexAKI (AKI)1.10.047822241LC-MS/MS24172336
Exp25150443aHomo sapiens24urinesupernatantNephrotic_Syndrome (paediatric idiopathic nephrotic syndrome)102.31.30E-03LC-MS25150443

Compile date 08-10-2018© iMODE-CKD consortium