CKDdb-logoCKDdb - Molecule ID A0230

geneARPC5, ARC16
nameARP2/3 complex 16 kDa subunit
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARPC5_HUMANO15511ENSP0000029474210092Hs.518609604227

Functions and classifications

GOC:Arp2/3 protein complex, C:cell projection, C:cytosol, F:structural constituent of cytoskeleton, P:actin cytoskeleton organization, P:cellular component movement, P:Fc-gamma receptor signaling pathway involved in phagocytosis, P:innate immune response, P:regulation of actin filament polymerization, C:cytoskeleton, C:cytoplasm
UniProtAcetylation, Actin-binding, Alternative splicing, Cell projection, Complete proteome, Cytoplasm, Cytoskeleton, Direct protein sequencing, Reference proteome, Ubl conjugation
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)4.14< 0.05RNA microarray21752957
Exp22007191Rattus norvegicus20kidneyglomeruliDiabetes (Diabetic Nephropathy)0.720.0014LC-ESI-MS/MS22007191
Exp22007191Rattus norvegicus20kidneyglomeruliDiabetes (Diabetic Nephropathy)0.740.0002LC-ESI-MS/MS22007191
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.451.02E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium