CKDdb-logoCKDdb - Molecule ID A022G

geneCATSPER2
nameCation channel sperm-associated protein 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CTSR2_HUMANQ96P56ENSG00000166762117155Hs.662284607249, 611102

Functions and classifications

GOC:CatSper complex, C:cilium, F:calcium channel activity, F:voltage-gated ion channel activity, P:cell differentiation, P:multicellular organism reproduction, P:multicellular organismal development, P:sperm-egg recognition, P:spermatogenesis, C:integral component of membrane, F:ion channel activity, P:ion transmembrane transport, C:flagellar membrane, P:ciliary or flagellar motility, P:fertilization, P:sperm motility, C:integral to membrane, C:microtubule-based flagellum
UniProtAlternative splicing, Calcium, Calcium channel, Calcium transport, Cell membrane, Cell projection, Cilium, Complete proteome, Developmental protein, Differentiation, Flagellum, Ion channel, Ion transport, Membrane, Polymorphism, Reference proteome, Spermatogenesis, Transmembrane, Transmembrane helix, Transport, Voltage-gated channel
PADBchannel

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp23505438aHomo sapiens kidneyproximal tubular cellsDiabetes (diabetic nephropathy)0.650.001cDNA microarray23505438
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)2.812.20E-03RNA microarray26317775
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)4.331.99E-03RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium