CKDdb-logoCKDdb - Molecule ID A021G

geneCATSPER1
nameCation channel sperm-associated protein 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CTSR1_HUMANQ8NEC5ENSG00000175294117144Hs.189105606389, 612997

Functions and classifications

GOC:CatSper complex, C:cilium, F:voltage-gated calcium channel activity, P:cell differentiation, P:ciliary or bacterial-type flagellar motility, P:fusion of sperm to egg plasma membrane, P:multicellular organism reproduction, P:multicellular organismal development, P:regulation of calcium ion transport, P:sperm motility, P:sperm-egg recognition, P:spermatogenesis, C:flagellar membrane, P:ciliary or flagellar motility
UniProtCalcium, Calcium channel, Calcium transport, Cell membrane, Cell projection, Cilium, Complete proteome, Developmental protein, Differentiation, Flagellum, Ion channel, Ion transport, Membrane, Polymorphism, Reference proteome, Spermatogenesis, Transmembrane, Transmembrane helix, Transport, Voltage-gated channel
PADBCNL: channel

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.248.15E-04RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.150.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium