CKDdb-logoCKDdb - Molecule ID A0121

geneAMPH, AMPH1
nameAmphiphysin I
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AMPH_HUMANP49418ENSG00000078053273Hs.592182600418

Functions and classifications

GOC:actin cytoskeleton, C:cell junction, C:leading edge membrane, C:synaptic vesicle, C:synaptic vesicle membrane, F:phospholipid binding, P:endocytosis, P:learning, P:synaptic transmission, P:synaptic vesicle endocytosis, C:cytoplasm, C:axon terminus, P:positive regulation of endocytosis, P:positive regulation of GTPase activity
UniProt3D-structure, Alternative splicing, Cell junction, Coiled coil, Complete proteome, Cytoplasm, Cytoplasmic vesicle, Cytoskeleton, Membrane, Phosphoprotein, Polymorphism, Reference proteome, SH3 domain, Synapse
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.370.033RNA microarray19698090
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.35< 0.05RNA microarray21752957
Exp24172336Mus musculus6kidneycortexAKI (AKI)4.90.022973399LC-MS/MS24172336
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.291.83E-03RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.130.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium