CKDdb-logoCKDdb - Molecule ID A0114

geneATP2B4, MXRA1
namePlasma membrane calcium-transporting ATPase 4
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AT2B4_HUMANP23634ENSG00000058668493Hs.343522108732

Functions and classifications

GOC:integral component of plasma membrane, C:protein complex, F:ATP binding, F:calcium-transporting ATPase activity, F:metal ion binding, F:scaffold protein binding, P:blood coagulation, P:negative regulation of peptidyl-cysteine S-nitrosylation, P:regulation of sodium ion transmembrane transport, C:integral component of membrane, P:ATP catabolic process, P:calcium ion transmembrane transport, C:integral to plasma membrane, P:ATP biosynthetic process, P:neural retina development, C:integral to membrane
UniProt3D-structure, Alternative splicing, ATP-binding, Calcium, Calcium transport, Calmodulin-binding, Cell membrane, Complete proteome, Direct protein sequencing, Hydrolase, Ion transport, Magnesium, Membrane, Metal-binding, Nucleotide-binding, Phosphoprotein, Reference proteome, Transmembrane, Transmembrane helix, Transport
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)4.29< 0.05RNA microarray21752957
Exp23935909Homo sapiens24bloodmonocytesChronic_Renal_Insufficiency (Chronic kidney disease)4.140.0194492RNA microarray23935909

Compile date 08-10-2018© iMODE-CKD consortium