CKDdb-logoCKDdb - Molecule ID A0078

speciesHomo sapiens

Molecule reference


Functions and classifications

GOC:extracellular region, C:extracellular space, C:integral component of membrane, C:plasma membrane, F:epidermal growth factor receptor binding, F:growth factor activity, P:epidermal growth factor receptor signaling pathway, P:Fc-epsilon receptor signaling pathway, P:fibroblast growth factor receptor signaling pathway, P:innate immune response, P:negative regulation of apoptotic process, P:neurotrophin TRK receptor signaling pathway, P:phosphatidylinositol-mediated signaling, P:positive regulation of cell differentiation, P:positive regulation of cell division, P:positive regulation of cell proliferation, P:positive regulation of fibroblast proliferation, P:positive regulation of mitosis, P:positive regulation of urine volume, C:integral to membrane
UniProt3D-structure, Cell membrane, Complete proteome, Disulfide bond, EGF-like domain, Glycoprotein, Growth factor, Membrane, Mitogen, Polymorphism, Reference proteome, Secreted, Signal, Transmembrane, Transmembrane helix

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603bMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)2.090cDNA microarray19099603
Exp22266139Homo sapiens kidneyproximal tubule epithelial cellsDiabetes (diabetic nephropathy)0.270.028577743NGS, RNA-seq.22266139

Compile date 08-10-2018© iMODE-CKD consortium