CKDdb-logoCKDdb - Molecule ID A0029

geneAnxa6
nameAnnexin A6
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ANXA6_MOUSEP14824ENSMUSG0000001834011749Mm.265347114070

Functions and classifications

GOC:extracellular vesicular exosome, C:melanosome, C:perinuclear region of cytoplasm, F:calcium ion binding, F:calcium-dependent phospholipid binding, P:calcium ion transport, P:regulation of muscle contraction, C:perinuclear region of cytoplasm, F:calcium ion binding, F:calcium-dependent phospholipid binding, P:calcium ion transport, P:regulation of muscle contraction, C:perinuclear region of cytoplasm, F:calcium ion binding, F:calcium-dependent phospholipid binding, P:calcium ion transport, P:regulation of muscle contraction, C:perinuclear region of cytoplasm, F:calcium ion binding, F:calcium-dependent phospholipid binding, P:calcium ion transport, P:regulation of muscle contraction, C:perinuclear region of cytoplasm, F:calcium ion binding, F:calcium-dependent phospholipid binding, P:calcium ion transport, P:regulation of muscle contraction, C:perinuclear region of cytoplasm, P:calcium ion transport, P:regulation of muscle contraction, C:perinuclear region of cytoplasm, F:calcium ion binding, F:calcium-dependent phospholipid binding, P:calcium ion transport, P:regulation of muscle contraction
UniProtAcetylation, Annexin, Calcium, Calcium/phospholipid-binding, Complete proteome, Cytoplasm, Direct protein sequencing, Phosphoprotein, Reference proteome, Repeat, Annexin, Calcium, Calcium/phospholipid-binding, Repeat, Annexin, Calcium, Calcium/phospholipid-binding, Repeat, Annexin, Calcium, Calcium/phospholipid-binding, Repeat, Annexin, Calcium, Calcium/phospholipid-binding, Repeat, , Annexin, Calcium, Calcium/phospholipid-binding, Complete proteome, Reference proteome, Repeat
PADBmodulator, regulator

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionValidationPubMed/DOI
Exp19688724Mus musculus kidneypodocytesHigh_glucose_induced (High glucose in vitro model)0< 0.05MALDI-TOF-MSqRT-PCR, Western blot, immunostaining19688724
Exp19845401Mus musculus32eyesretinaDiabetes (diabetic retinopathy)3.3< 0.05LC-MS/MS 19845401
Exp20093355Homo sapiens33kidney Fibrosis (Interstitial fibrosis and tubular atrophy)up MS/MS, LTQ LX linear ion trap 20093355
Exp20940332Mus musculus kidneycollecting duct cellsVasopressine_induced (Vasopressine in vitro model)0.71< 0.05LC-MS/MS 20940332
Exp23344851Rattus norvegicus14urineexosomeDiabetes (diabetic nephropathy)1.13 nLC-ESI-UHR-QToF-MS/MS 23344851
Exp24172336Mus musculus6kidneycortexAKI (AKI)1.350.022499604LC-MS/MS 24172336
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)4.079.49E-04RNA microarray 26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)7.890.004443RNA microarray 26317775

Compile date 08-10-2018© iMODE-CKD consortium