CKDdb-logoCKDdb - Molecule ID A0011

geneCAMK2A, CAMKA
nameCalcium/calmodulin-dependent protein kinase type II alpha chain
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
KCC2A_HUMANQ9UQM7ENSG00000070808815Hs.743976114078

Functions and classifications

GOC:cell junction, C:cytosol, C:endocytic vesicle membrane, C:nucleoplasm, C:plasma membrane, C:presynaptic membrane, F:ATP binding, F:calmodulin-dependent protein kinase activity, F:kinase activity, P:calcium ion transport, P:G1/S transition of mitotic cell cycle, P:interferon-gamma-mediated signaling pathway, P:positive regulation of NF-kappaB transcription factor activity, P:protein autophosphorylation, P:protein phosphorylation, P:regulation of neuronal synaptic plasticity, P:regulation of neurotransmitter secretion, P:synaptic transmission, C:calcium- and calmodulin-dependent protein kinase complex, F:protein serine/threonine kinase activity
UniProt3D-structure, Alternative splicing, ATP-binding, Calmodulin-binding, Cell junction, Cell membrane, Complete proteome, Kinase, Membrane, Nucleotide-binding, Phosphoprotein, Reference proteome, Serine/threonine-protein kinase, Synapse, Transferase
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.210.000586RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.310.000000554RNA microarray19698090

Compile date 08-10-2018© iMODE-CKD consortium