PADB-logoLSSR - molecule cluster A7015MGAM, MGA, MGAMLMaltase-glucoamylase, intestinal

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensMGA_HUMANO434511857209852154360

Functions and Classifications

GOC:apical plasma membrane, C:integral component of membrane, C:plasma membrane, F:alpha-glucosidase activity, F:amylase activity, F:carbohydrate binding, F:glucan 1,4-alpha-glucosidase activity, F:maltose alpha-glucosidase activity, P:polysaccharide digestion, P:small molecule metabolic process, P:starch catabolic process, P:metabolic process, "F:carbohydrate binding, F:hydrolase activity, hydrolyzing O-glycosyl compounds, P:carbohydrate metabolic process", C:integral to membrane, P:carbohydrate metabolic process
UniProt3D-structure, Cell membrane, Complete proteome, Direct protein sequencing, Disulfide bond, Glycoprotein, Glycosidase, Hydrolase, Membrane, Multifunctional enzyme, Polymorphism, Reference proteome, Repeat, Signal-anchor, Sulfation, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Expression

percent [in mouse]
cerebrumcerebellumbrainstemspinal cordkidneyliverheartskeletal muscleadiposestomachsmall intestinelarge intestinetestisplacenta
0, 0, 04, 0, 00, 25, 00, 0, 00, 0, 00, 0, 00, 0, 00, 0, 00, 0, 00, 0, 084, 75, 904, 0, 30, 0, 08, 0, 7

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
16948836humanurinewhole healthy     
16316981humanurinewhole healthy     
16684767humanbloodplasma severe trauma     Identified peptides: 1
16709260humansemenplasma healthy     
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
17711322humankidneyglomerulus healthy     
15593129ratkidneyrenal cortex, basolateral membrane vesicles healthy     
15593129ratkidneyrenal cortex, basolateral membrane vesicles healthy     
17711322humankidneyglomerulus healthy     
20198343humanurinewhole cancer -weight losing     
16281181humanurinewhole healthy     
15326289humanurineexosomeplasma membranehealthy     
17518487humanurinewholemembrane bladder cancer     
18373357humanurinemicroparticles bladder cancer   1 
21127740humanurinewhole acute abdominal pain     Identified peptides: 376
UNPUBLISHED_1humanurinewhole cancer     
23376485humanurinepodocyte healthy     
23376485humanurinepodocyte healthy     

Compile date 12-23-2014© PADB initiative