PADB-logoLSSR - molecule cluster A5939BPNT1, PIP3'(2'),5'-Bisphosphate nucleotidase 1

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensBPNT1_HUMANO9586130833392604053

Functions and Classifications

GOC:cytosol, F:3'(2'),5'-bisphosphate nucleotidase activity, F:inositol-1,4-bisphosphate 1-phosphatase activity, F:magnesium ion binding, P:3'-phosphoadenosine 5'-phosphosulfate metabolic process, P:nervous system development, P:phosphatidylinositol phosphorylation, P:xenobiotic metabolic process, "F:3'(2'),5'-bisphosphate nucleotidase activity, P:dephosphorylation, P:phosphatidylinositol phosphorylation"
UniProt3D-structure, Acetylation, Alternative splicing, Complete proteome, Hydrolase, Lithium, Magnesium, Metal-binding, Reference proteome
PADBENZ: enzyme, enzymatic properties

Expression

percent [in mouse]
cerebrumcerebellumbrainstemspinal cordkidneyliverheartskeletal muscleadiposestomachsmall intestinelarge intestinetestisplacenta
71012295005928742

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
16948836humanurinewhole healthy     
18501002mousekidneycortexNucleushealthy     
16709260humansemenplasma healthy     
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
21616181mousecornea  lumican knock-out   0.765 
16449382ratkidneyinner medullary collecting duct (IMCD) Flow through proteins from avidin affinity step of technique 4     
16615899mouseliverorganelleCytosol (Cyto)healthy     
15951573humanlungbronchoalveolar lavage asthma     
16083270humanlungwhole smoker     
16518875humannasalnasal cellsCytoplasmcystic fibrosis     
15684408mouseplasma membranebrain cortex and hippocampus healthy     
15064947humantestiswhole healthy     
18582094mousetestiswhole healthy     
23376485humanurinepodocyte healthy     
23376485humanurinepodocyte healthy     
18553995humanprostatewhole prostate cancer     Identified peptides: 4

Compile date 12-23-2014© PADB initiative