PADB-logoLSSR - molecule cluster A5528CD63, MLA1, TSPAN30CD63 antigen

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensCD63_HUMANP0896223725505155740

Functions and Classifications

GOC:cell surface, C:endosome membrane, C:integral component of plasma membrane, C:late endosome membrane, C:lysosomal membrane, C:platelet dense granule membrane, P:cellular protein localization, P:platelet activation, P:platelet degranulation, P:regulation of rubidium ion transport, C:integral component of membrane, C:late endosome, C:lysosome, C:integral to membrane, C:integral to plasma membrane, C:protein complex, P:epithelial cell differentiation, P:negative regulation of epithelial cell migration, P:positive regulation of cell adhesion, P:positive regulation of endocytosis, C:plasma membrane
UniProtAlternative splicing, Cell membrane, Complete proteome, Direct protein sequencing, Endosome, Glycoprotein, Lysosome, Membrane, Reference proteome, Transmembrane, Transmembrane helix
PADBTM: transmembrane

Expression

percent [in mouse]
cerebrumcerebellumbrainstemspinal cordkidneyliverheartskeletal muscleadiposestomachsmall intestinelarge intestinetestisplacenta
0, 00, 00, 00, 00, 00, 00, 00, 00, 00, 00, 00, 011, 1189, 89

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
16948836humanurinewhole healthy     
16709260humansemenplasma healthy     
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
9685355humanB-lymphocyteexosomeplasma membranehealthy     
9585234humandendritic cellexosomeplasma membranehealthy     
12096030humandendritic cellexosomeplasma membranehealthy     
12724530humanHela cell extractlipid raftsdetergent-resistant rafthealthy      
15951573humanlungbronchoalveolar lavage asthma     
10572093humanplateletexosomeplasma membranehealthy     
11907077humanT cellexosomeplasma membranehealthy     
15326289humanurineexosomeplasma membranehealthy     
11487543humanurineexosomeplasma membranehealthy     
18373357humanurinemicroparticles bladder cancer   2.3 
21127740humanurinewhole acute abdominal pain     Identified peptides: 11
23376485humanurinepodocyte healthy     
23376485humanurinepodocyte healthy     
20334419humanprostateprostate secretion healthy     
19056867humanurineexosome healthy     Identified peptides: 2
19056867humanurineexosome healthy     Identified peptides: 1

Compile date 12-23-2014© PADB initiative