PADB-logoLSSR - molecule cluster A513AHIST2H2BE, H2BFQ, H2B.1Histone H2B type 2-E

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensH2B2E_HUMANQ1677812513789601831

Functions and Classifications

GOC:nucleosome, C:nucleus, F:DNA binding, P:defense response to bacterium, P:nucleosome assembly
UniProtAcetylation, Antibiotic, Antimicrobial, Chromosome, Complete proteome, Direct protein sequencing, DNA-binding, Glycoprotein, Isopeptide bond, Methylation, Nucleosome core, Nucleus, Phosphoprotein, Reference proteome, Ubl conjugation
PADBTF: transcription and translation, gene regulation

Expression

percent [in mouse]
cerebrumcerebellumbrainstemspinal cordkidneyliverheartskeletal muscleadiposestomachsmall intestinelarge intestinetestisplacenta
0, 02, 20, 00, 00, 03, 40, 13, 26, 68, 854, 563, 31, 120, 18

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
16709260humansemenplasma healthy     
16446289humanhairshaft healthy     
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
15169875rat; mousebrainPSD (whole brain) healthy     
15169875rat; mousebrainPSD (whole brain) healthy     
15169875rat; mousebrainPSD (whole brain) healthy     
15169875rat; mousebrainPSD (whole brain) healthy     
16381850humanHela cell extractnucleus healthy     theoretical Mr: 13781
17711322humankidneyglomerulus healthy     
16335936humanurinewhole healthy     
18373357humanurinemicroparticles bladder cancer   0.6 
UNPUBLISHED_1humanurinewhole cancer     
18578523humanPC3 cancer cellsecretion       
UNPUBLISHED_3humanPC3 cancer cellwhole        
18553995humanprostatewhole prostate cancer     Identified peptides: 5

Compile date 12-23-2014© PADB initiative