PADB-logoLSSR - molecule cluster A4332HSPA4L, APG1, OSP94Osmotic stress protein 94

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensHS74L_HUMANO9575783994486 

Functions and Classifications

GOC:cytoplasm, C:nucleus, F:ATP binding, P:protein folding, P:response to unfolded protein, P:response to stress
UniProtATP-binding, Chaperone, Complete proteome, Cytoplasm, Nucleotide-binding, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Stress response
PADBCHA: chaperone, chaperonin

Expression

percent [in mouse]
cerebrumcerebellumbrainstemspinal cordkidneyliverheartskeletal muscleadiposestomachsmall intestinelarge intestinetestisplacenta
714541400000000110

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
16684767humanbloodplasma severe trauma     Identified peptides: 3
16709260humansemenplasma healthy     
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
21170055humanbrainPSD (neocortex) Glial neoplasm/Lesional epilepsy/Colloid cyst     Unique peptides: 7
16449382ratkidneyinner medullary collecting duct (IMCD) Flow through proteins from avidin affinity step of technique 4     
16615899mouseliverorganelle healthy     
18582094mousetestiswhole healthy     
18582094mousetestiswhole healthy     
18582094mousetestiswhole healthy     
18582094mousetestiswhole healthy     
18582094mousetestiswhole healthy     
15064947humantestiswhole healthy     
15064947humantestiswhole healthy     
15064947humantestiswhole healthy     
UNPUBLISHED_2sheepbrainfrontal cortex healthy     
UNPUBLISHED_2sheepbrainfrontal cortex healthy     
UNPUBLISHED_2sheepbrainfrontal cortex healthy     
UNPUBLISHED_2sheepbrainhippocampus healthy     
UNPUBLISHED_2sheepbrainhippocampus healthy     
UNPUBLISHED_2sheepbrainhippocampus healthy     
UNPUBLISHED_3humanPC3 cancer cellwhole        

Compile date 12-23-2014© PADB initiative