PADB-logoLSSR - molecule cluster A424AFHL1, SLIM1Skeletal muscle LIM-protein 1

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensFHL1_HUMANQ1364232336263300163, 300695, 300696, 300717, 300718

Functions and Classifications

GOC:cytoplasm, C:cytosol, C:nucleus, C:plasma membrane, F:zinc ion binding, P:cell differentiation, P:muscle organ development, P:negative regulation of cell growth, P:negative regulation of G1/S transition of mitotic cell cycle, P:negative regulation of G2/M transition of mitotic cell cycle, P:organ morphogenesis, P:positive regulation of potassium ion transport, P:regulation of membrane depolarization, P:regulation of potassium ion transmembrane transporter activity, F:metal ion binding
UniProt3D-structure, Alternative splicing, Complete proteome, Cytoplasm, Developmental protein, Differentiation, Direct protein sequencing, Disease mutation, LIM domain, Metal-binding, Nucleus, Reference proteome, Repeat, Zinc, Zinc-finger, Cardiomyopathy
PADBTF: transcription and translation, gene regulation

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
18501002mousekidneycortexCytoplasmhealthy     
16684767humanbloodplasma severe trauma     Identified peptides: 7
16709260humansemenplasma healthy     
15253431humanheartmitochondria healthy     Unique peptides: 1
16507876ratbrainPSD (forebrain and cerebellum) healthy     Identified peptides: 1
17711322humankidneyglomerulus healthy     
17711322humankidneyglomerulus healthy     
17711322humankidneyglomerulus healthy     
17711322humankidneyglomerulus healthy     
17711322humankidneyglomerulus healthy     
17711322humankidneyglomerulus healthy     
17711322humankidneyglomerulus healthy     
17711322humankidneyglomerulus healthy     
15951573humanlungbronchoalveolar lavage asthma     
UNPUBLISHED_3humanPC3 cancer cellwhole        
18553995humanprostatewhole prostate cancer     Identified peptides: 6
18725486mouselungwhole lung pulmonary hypertension   6.6 

Compile date 12-23-2014© PADB initiative