PADB-logoLSSR - molecule cluster A3846KRT6C, KRT6E, KRT6DKeratin, type II cytoskeletal 6C

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensK2C6C_HUMANP4866856360092612315

Functions and Classifications

GOC:intermediate filament, C:keratin filament, F:structural molecule activity, P:cytoskeleton organization
UniProtAcetylation, Coiled coil, Complete proteome, Direct protein sequencing, Intermediate filament, Keratin, Phosphoprotein, Polymorphism, Reference proteome
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
16684767humanbloodplasma severe trauma     Identified peptides: 10
16709260humansemenplasma healthy     
18361515humansalivaParotid;SMSL healthy     
15169875rat; mousebrainPSD (whole brain) healthy     
15169875rat; mousebrainPSD (whole brain) healthy     
12724530humanHela cell extractlipid raftsdetergent-resistant rafthealthy      
18324733raturinewhole healthy     
18373357humanurinemicroparticles bladder cancer   0.8 
21127740humanurinewhole acute abdominal pain     Identified peptides: 653
21538913humanurinewhole cancer (upper GI)     
UNPUBLISHED_1humanurinewhole healthy, cancer     
UNPUBLISHED_3humanPC3 cancer cellwhole        

Compile date 12-23-2014© PADB initiative