PADB-logoLSSR - molecule cluster A3693CKB, CKBBCreatine kinase B-type

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensKCRB_HUMANP1227738142644123280

Functions and Classifications

GOC:cytosol, C:mitochondrion, F:ATP binding, F:creatine kinase activity, P:brain development, P:cellular chloride ion homeostasis, P:cellular nitrogen compound metabolic process, P:creatine metabolic process, F:kinase activity, P:phosphorylation
UniProt3D-structure, ATP-binding, Complete proteome, Cytoplasm, Direct protein sequencing, Kinase, Nitration, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, Transferase
PADBENZ: enzyme, enzymatic properties

Expression

percent [in mouse]
cerebrumcerebellumbrainstemspinal cordkidneyliverheartskeletal muscleadiposestomachsmall intestinelarge intestinetestisplacenta
14113171001112201515

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
16948836humanurinewhole healthy     
16684767humanbloodplasma severe trauma     Identified peptides: 6
16709260humansemenplasma healthy     
17381150humannasalolfactory cleft mucus (nasal mucus) healthy     
18361515humansalivaParotid healthy     Identified peptides: 3
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
16507876ratbrainPSD (forebrain and cerebellum) healthy     Identified peptides: 3
15020595ratbrainPSD (forebrain) healthy     
21616181mousecornea  lumican knock-out   0.945 
1629737bovinebrainPSD cerebral cortex healthy      
21170055humanbrainPSD (neocortex) Glial neoplasm/Lesional epilepsy/Colloid cyst     Unique peptides: 23
15169875rat; mousebrainPSD (whole brain) healthy     
15169875rat; mousebrainPSD (whole brain) healthy     
15169875rat; mousebrainPSD (whole brain) healthy     
15169875rat; mousebrainPSD (whole brain) healthy     
14532281ratbrainPSD forebrain healthy     
15169875rat; mousebrainPSD (whole brain) healthy     
16047384ratbrainPSD pre- and postsynapse (cortex)postsynaptichealthy     Sequence coverage: 7.9
15169875rat; mousebrainPSD (whole brain) healthy     
15169875rat; mousebrainPSD (whole brain) healthy     
15169875rat; mousebrainPSD (whole brain) healthy     
15852343ratbrainPSD cerebral cortex (frontal) healthy     
12965894ratkidneyinner medullary collecting duct (IMCD) IMCD vs. non-IMCD protein amounts     
16449382ratkidneyinner medullary collecting duct (IMCD) 3 day Vasopressin infusion to Brattleboro rat   1.34 0.07 
16449382ratkidneyinner medullary collecting duct (IMCD) Flow through proteins from avidin affinity step of technique 4     
15951573humanlungbronchoalveolar lavage asthma     
16021519humanovarywhole healthy     
15064947humantestiswhole healthy     
15064947humantestiswhole healthy     
17022654humanurinewhole healthy     
15529407humanurinewhole healthy     
15529407humanurinewhole healthy     
16335936humanurinewhole healthy     
18373357humanurinemicroparticles bladder cancer   0.4 
21127740humanurinewhole acute abdominal pain     Identified peptides: 41
23376485humanurinepodocyte healthy     
23376485humanurinepodocyte healthy     
UNPUBLISHED_2sheepbrainfrontal cortex healthy     
UNPUBLISHED_2sheepbrainfrontal cortex healthy     
UNPUBLISHED_2sheepbrainfrontal cortex healthy     
UNPUBLISHED_2sheepbrainhippocampus healthy     
UNPUBLISHED_2sheepbrainhippocampus healthy     
UNPUBLISHED_2sheepbrainhippocampus healthy     
18553995humanprostatewhole prostate cancer     Identified peptides: 12
20334419humanprostateprostate secretion healthy     
19056867humanurineexosome healthy     Identified peptides: 8
22234359ratheartleft ventricles spontaneous hypertension   2.07 
22234359ratheartleft ventricles spontaneous hypertension   2.07 
22234359ratheartleft ventricles diabetes and hypertension   1.65 
22234359ratheartleft ventricles diabetes and hypertension   1.65 
22234359ratheartleft ventricles diabetes and hypertension   1.38 
22234359ratheartleft ventricles diabetes and hypertension   1.38 
16485256ratheartleft ventricle spontaneous hypertension   2.3+/-0.8 
16485256ratheartleft ventricle spontaneous hypertension   4.2+/-1.9 
16485256ratheartleft ventricle spontaneous hypertension   4.2+/-2 

Compile date 12-23-2014© PADB initiative