PADB-logoLSSR - molecule cluster A1613C2Complement C2 precursor

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensCO2_HUMANP0668175283268217000, 603075, 613927

Functions and Classifications

GOC:extracellular space, F:serine-type endopeptidase activity, P:complement activation, classical pathway, P:innate immune response, P:proteolysis, P:regulation of complement activation, C:extracellular region, P:complement activation, F:metal ion binding
UniProt3D-structure, Alternative splicing, Complement pathway, Complete proteome, Direct protein sequencing, Disease mutation, Disulfide bond, Glycoprotein, Hydrolase, Immunity, Innate immunity, Polymorphism, Protease, Reference proteome, Repeat, Secreted, Serine protease, Signal, Sushi, Magnesium, Manganese, Metal-binding
PADBENZ: enzyme, enzymatic properties

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
16948836humanurinewhole healthy     
16684767humanbloodplasma severe trauma     Identified peptides: 114
16709260humansemenplasma healthy     
17711322humankidneyglomerulus healthy     
17711322humankidneyglomerulus healthy     
17711322humankidneyglomerulus healthy     
17711322humankidneyglomerulus healthy     
16691549ratliverGolgi healthy      
15951573humanlungbronchoalveolar lavage asthma     
15140760humanurinewhole Dent's disease   9.1+/-0.7  
20334419humanprostateprostate secretion healthy     

Compile date 12-23-2014© PADB initiative